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Do I need to register with Grants.gov?

No...

No, the University of Maryland is registered an an organization in Grants.gov. PIs and other project personnel do not need accounts in Grants.gov. ORAA and the MPRC team will submit all Grants.gov application packages on behalf of the university and track the status of submissions through Grants.gov. Please note that all PIs on an NIH proposal must be registered with NIH's eRA Commons.