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Exposure to Particulate Matter and Adverse Birth Outcomes: A Comprehensive Review and Meta Analysis.
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Increasing number of studies have investigated the impact of maternal exposure to air pollution during pregnancy and adverse birth outcomes, particularly low birth weight (LBW, <2,500 g at birth) and preterm birth (PTB, <37 completed weeks of gestation). We performed a comprehensive review of the peer-reviewed literature and a meta-analysis to quantify the association between maternal exposure to particulate matter with aerodynamic diameter 2.5 and 10 μm (PM 2.5 and PM 10 ) during pregnancy and the risk of LBW and PTB. We identified 20 peer-reviewed articles providing quantitative estimate of exposure and outcome that met our selection criteria. There was significant heterogeneity between studies, particularly for findings related to PM 10 exposure (LBW, I -squared 54%, p = 0.01; PTB, I -squared = 73%, p < 0.01). Results from random-effect meta-analysis suggested a 9% increase in risk of LBW associated with a 10-μg/m 3 increase in PM 2.5 (combined odds ratios (OR), 1.09; 95% confidence interval (CI), 0.90–1.32), but our 95% CI included the null value. We estimated a 15% increase in risk of PTB for each 10-μg/m 3 increase in PM 2.5 (combined OR, 1.15; CI, 1.14–1.16). The magnitude of risk associated with PM 10 exposure was smaller (2% per 10-μg/m 3 increase) and similar in size for both LBW and PTB, neither reaching formal statistical significance. We observed no significant publication bias, with p > 0.05 based on both Begg's and Egger's bias tests. Our results suggest that maternal exposure to PM, particularly PM 2.5 may have adverse effect on birth outcomes. Additional mechanistic studies are needed to understand the underlying mechanisms for this association.
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MPRC People
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Amir Sapkota, Ph.D.
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Amir Sapkota Publications
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Self-rated Health and Structural Racism Indicated by County-level Racial Inequalities in Socioeconomic Status: The Role of Urbanization
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Caryn N. Bell University of Maryland: Jessica L. Owens-Young American University: 2019-005
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Research
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Working Papers
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WP Documents
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The role of weight perception in race differences in body mass index by education among women
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Caryn N. Bell University of Maryland: Loneke T. Blackman Carr Duke University: 2019-006
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Research
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Working Papers
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WP Documents
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Wade Jacobsen, UMD Criminology
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Juvenile Arrest and Interpersonal Exclusion: Rejection, Withdrawal, and Homophily among Peers
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Coming Up
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Structural Racism and Population Health: The Role of Race, Socioeconomic Status and Context
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Caryn Bell, African American Studies, examines the effects of macro-level structural racism on population health
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Seed Grant Program
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Seed Grants Awarded
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Population Health Trends among Hetrosexual and Sexual Minority Adults
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Jessica N. Fish, Family Science, investigates sexual-orientation-related disparities in mental, behavioral, and physical health
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Seed Grant Program
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Seed Grants Awarded
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Utilizing Student Health and Academic Data: A County-Level Demonstration Project
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Students with chronic health conditions miss more school days than their peers and are at increased risk for performing worse on standardized tests and not completing a high school degree. University-based researchers, state government leaders, and a local county school system collaborated to use existing health and academic data to (1) evaluate the strength of the relationship between health status and school performance (absenteeism, grades) and (2) describe the health status of students who are chronically absent. Analyses included descriptive statistics, chi-square tests, negative binomial regression models, and estimated marginal means. The most common health conditions among the 3,663 kindergarten through Grade 12 students were ADD (attention deficit disorder)/ADHD (attention deficit hyperactivity disorder), asthma, migraine headaches, mental health conditions, and eczema/psoriasis/skin disorders. After controlling for covariates, having asthma or a mental health diagnosis was positively associated with absences; and having an ADD/ADHD or mental health diagnosis was negatively associated with GPA (grade point average). Chronically absent students had significantly lower GPAs, and a higher number of health conditions than other students. The success of this demonstration project encourages strengthening existing collaborations and establishing new multidisciplinary partnerships to analyze existing data sources to learn more about the relationship between student health and academic achievement. Moreover, connecting health status to academic achievement might be a chief tactic for advocating for additional resources to improve the care and management of chronic disease conditions among students.
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MPRC People
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Olivia Denise Carter-Pokras, Ph.D.
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Olivia Denise Carter-Pokras Publications
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Steven Haas, Penn State University
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The Long-Arm of Conflict: How Timing Shapes the Long-term Impacts of Childhood Exposure to War
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Coming Up
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Amanda Geller, New York University
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Police Contact, Mental Health, and Health Disparities among Urban Teens
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Coming Up
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Michael White, Brown University
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Migration, Urbanization, and Health: Insights from South Africa
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Coming Up